成果/Result
- Structural repurposing of SGLT2 inhibitor empagliflozin for strengthening anti-heart failure activity with lower glycosuria被引量:3收藏
- 作者:Yixiang Xu Chao Zhang Kai Jiang Xinchun Yang Feng Chen Zhiyang Cheng Jinlong Zhao Jiaxing Cheng Xiaokang Li Xin Chen Luoyifan Zhou Hao Duan Yunyuan Huang Yaozu Xiang Jian Li
- 机构:State Key Laboratory of Bioreactor Engineering;Shanghai East Hospital;East China University of Science and Technology-Tengbai Pharmaceutical Innovative Drugs Joint Research Institute;Hubei Key Laboratory of Genetic Regulation and Integrative Biology;Yunnan Key Laboratory of Screening and Research on Anti-pathogenic Plant Resources from West Yunnan
- 来源:药学学报(英文版) 2023
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- Discovery of synergistic activity of fluoroquinolones in combination with antimicrobial peptides against clinical polymyxin-resistant Pseudomonas aeruginosa DK2被引量:2收藏
- 作者:Xinyu Zheng Qiao Cao Qin Cao Fei Mao Xiaokang Li Jin Zhu Lefu Lan Jian Li
- 机构:State Key Laboratory of Bioreactor Engineering;State Key Laboratory of Drug Research
- 来源:中国化学快报(英文版) 2020
- 关键词:Polymyxin B Pseudomonas aeruginosa Fluoroquinolones Synergy Cystic fibrosis Antimicrobial peptides
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- Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer’s disease被引量:2收藏
- 作者:Xiaokang Li Jian Lu Yixiang Xu Jiaying Wang Xiaoxia Qiu Lei Fan Baoli Li Wenwen Liu Fei Mao Jin Zhu Xu Shen Jian Li
- 机构:State Key Laboratory of Bioreactor Engineering;School of Medicine and Life Sciences;Center for Drug Safety Evaluation and Research
- 来源:药学学报(英文版) 2020
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- Repurposing of antitumor drug candidate Quisinostat lead to novel spirocyclic antimalarial agents被引量:1收藏
- 作者:Ruoxi Li Dazheng Ling Tongke Tang Zhenghui Huang Manjiong Wang Fei Mao Jin Zhu Lubin Jiang Jian Li Xiaokang Li
- 机构:State Key Laboratory of Bioreactor Engineering;Key Laboratory of Molecular Virology and Immunology;College of Pharmacy and Chemistry;Frontiers Science Center for Materiobiology and Dynamic Chemistry;School of Life Science and Technology
- 来源:中国化学快报(英文版) 2021
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- Specific tracking of monoamine oxidase A in heart failure models by a far-red fluorescent probe with an ultra large Stokes shift被引量:1收藏
- 作者:Xinming Li Donglei Shi Yihe Song Yixiang Xu Ying Gao Wenjing Qiu Xin Chen Xiaokang Li Yunyuan Huang Yanjun Feng Baoli Li Yuan Guo Jian Li
- 机构:State Key Laboratory of Bioreactor Engineering;Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education;Frontiers Science Center for Materiobiology and Dynamic Chemistry;College of Pharmacy and Chemistry;Clinical Medicine Scientific and Technical Innovation Center
- 来源:中国化学快报(英文版) 2022
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