成果/Result
- Mechanistic insight into the disruption of Tau R3-R4 protofibrils by curcumin and epinephrine: an all-atom molecular dynamics study被引量：24收藏
- 作者：Zou, Yu Qi, Bote Tan, Jingwang Sun, Yunxiang Gong, Yehong Zhang, Qingwen
- 机构：Zhejiang Univ;Fudan Univ;Fudan Univ;Ningbo Univ;East China Univ Sci & Technol
- 来源：PHYSICAL CHEMISTRY CHEMICAL PHYSICS 2022
- 关键词：Aggregates - Binding energy - Hydrogen bonds - Hydrophobicity - Molecules - Positive ions
- The destructive mechanism of Aβ1-42 protofibrils by norepinephrine revealed via molecular dynamics simulations被引量：15收藏
- 作者：Gao, Duo Wan, Jiaqian Zou, Yu Gong, Yehong Dong, Xuewei Xu, Zhengdong Tang, Jiaxing Wei, Guanghong Zhang, Qingwen
- 机构：Shanghai Univ Sport;Zhejiang Univ;East China Univ Sci & Technol;Fudan Univ;Fudan Univ
- 来源：PHYSICAL CHEMISTRY CHEMICAL PHYSICS 2022
- 关键词：Medical imaging - Molecular dynamics - Neurodegenerative diseases - Norepinephrine - Protonation
- destabilization mechanism of R3-R4 tau protofilament by purpurin: a molecular dynamics study被引量：3收藏
- 作者：Wan, Jiaqian Zou, Yu Sun, Ruiqing Xu, Zhengdong Tang, Jiaxing Gong, Yehong Wei, Guanghong Zhang, Qingwen
- 机构：Shanghai Univ Sport;Zhejiang Univ;East China Univ Sci & Technol;Fudan Univ;Fudan Univ
- 来源：PHYSICAL CHEMISTRY CHEMICAL PHYSICS 2023
- 关键词：Aggregates - Ketones - Neurodegenerative diseases
