文献类型：期刊文献

英文题名：Bioavailability and release of nonextractable (bound) residues of chiral cycloxaprid using geophagous earthworm Metaphire guillelmi in rice paddy soil

作者：Liu, Xuanqi[1];Xu, Xiaoyong[1];Zhang, Hanxue[2];Li, Chao[1];Shao, Xusheng[1];Ye, Qingfu[2];Li, Zhong[1]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Zhejiang Univ, Inst Nucl Agr Sci, Hangzhou 310029, Zhejiang, Peoples R China

年份：2015

卷号：526

起止页码：243

外文期刊名：SCIENCE OF THE TOTAL ENVIRONMENT

收录：;EI(收录号：20151800806863);WOS:【SCI-EXPANDED(收录号:WOS:000356224100024)】；

基金：This work was financial supported by the Fundamental Research Funds for the Central Universities and Special Fund for Agro-scientific Research in the Public Interest (201103007). This work was also partly supported by the National High Technology Research and Development Program of China (863 Program, 2011AA10A207 and 2013AA065202).

语种：英文

外文关键词：Cycloxaprid; Enantiomers; Bound residues; Release; Bioavailability; Depuration

摘要：The widespread adoption of neonicotinoids has led to a move away from integrated pest management (IPM) and caused adverse effects on non-target invertebrate species. Due to their living in close contact with and consuming large amounts of soil, earthworms are a model organism used to study bioaccumulation. We investigated the bioaccumulation and release of bound, or non-extractable, residues (BRs) of C-14 labeled racemic cycloxaprid (CYC) and its individual enantiomers by the geophagous earthworm Metaphire guillelmi. In a previous work, the fraction of BRs of C-14-CYC individual enantiomers reached up to 70-85% of the initially spiked radioactivity after 100 d of treatment. The bulk volume of the soil was then diluted by a factor of 15 with fresh soil. Here we showed that after earthworms lived in the soil-bound residues for 28 d, 11-25% of the previously bound radioactivity in soil was extractable by solvent, mineralized to CO2, and accumulated in earthworm tissues. While earthworms were exposed to C-14-CYC a two-compartment accumulation model could explain the bio-accumulation as individual enantiomers. At the end of the experiment, the biota-sediment accumulation factors were between 0.59 and 0.82, which suggested CYC immobilization in the soil resulted in its bioavailability being reduced which enhanced its degradation. Additionally, the elimination of CYC individual enantiomers from M. guillelmi was fitted to an availability-adjusted decay model with a half-life of 9 d. Stereoselective release or bioavailability between CYC enantiomers was not observed. These results provide the important data about the release of BRs of CYC and potential transfer in the food chain to support the long-term environmental risk assessment of neonicotinoids. (C) 2015 Elsevier B.V. All rights reserved.