详细信息

Method for preparing polyethylene glycol-poly (gamma-amino-(epsilon) caprolactone) nanoparticles used as carrier for hydrophilic medicine, involves adding aminoether compound and polycyclic compound in water    

文献类型:专利

英文题名:Method for preparing polyethylene glycol-poly (gamma-amino-(epsilon) caprolactone) nanoparticles used as carrier for hydrophilic medicine, involves adding aminoether compound and polycyclic compound in water

作者:LANG M;LIU J;ZHANG Y;YAN J

机构:[1]UNIV EAST CHINA SCI&TECHNOLOGY

申请号:CN102327227-B

公开日:2012-12-05

语种:英文

收录:DERWENT

摘要:NOVELTY - A polyethylene glycol-poly ( gamma -amino-( epsilon )caprolactone) nanoparticles preparing method involves adding aminoether compound (I) and polycyclic compound (II) separately in water to obtain solutions. The solutions are mixed to obtain mixed solution that is subjected to ultracentrifugation to obtain polyethylene glycol-poly ( gamma -amino-( epsilon ) caprolactone) nanoparticles. USE - Method for preparing a polyethylene glycol-poly ( gamma -amino-( epsilon ) caprolactone) nanoparticles used as a carrier for a hydrophilic medicine. DETAILED DESCRIPTION - A polyethylene glycol-poly ( gamma -amino-( epsilon )caprolactone) nanoparticles preparing method involves adding aminoether compound of formula (I) and polycyclic compound of formula (II) separately in water to obtain solutions. The solutions are mixed to obtain mixed solution that is subjected to ultracentrifugation to obtain polyethylene glycol-poly ( gamma -amino-( epsilon ) caprolactone) nanoparticles. x=45-227; y=10-100;and R1-R3=H or (NH4)+.

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