文献类型：期刊文献

英文题名：Enantioselective Rauhut-Currier-Type 1,6-Conjugate Addition of Methyl Vinyl Ketone to para-Quinone Methides

作者：Kang, Tian-Chen[1,2];Wu, Lu-Ping[1,2];Yu, Qi-Wen[1,2];Wu, Xin-Yan[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2017

卷号：23

期号：27

起止页码：6509

外文期刊名：CHEMISTRY-A EUROPEAN JOURNAL

收录：;EI(收录号：20171703596332);WOS:【SCI-EXPANDED(收录号:WOS:000401160100007)，CCR-EXPANDED(收录号:WOS:000401160100007)】；

基金：We are grateful for the financial support from Science and Technology Commission of Shanghai Municipality (15ZR1409200).

语种：英文

外文关键词：asymmetric catalysis; chiral phosphine; conjugation; quinone methide; rauhut-currier

摘要：An unprecedented Rauhut-Currier-type 1,6-conjugate addition has been developed. With chiral cyclohexane-based phosphine-amide catalyst 3h, the 1,6-conjugate reaction has been achieved to produce chiral diarylmethine compounds in excellent yields (91-99%) and enantioselectivities (92-98% ee).