文献类型：期刊文献

英文题名：Palladium-catalyzed cross-coupling of aryl chlorides with O, N-chelate stabilized diarylborinates

作者：Zhang, Nan[1];Wang, Chen[1];Zou, Gang[1];Tang, Jie[2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai, Peoples R China;[2]East China Normal Univ, Shanghai Engn Res Ctr Mol Therapeut & New Drug De, Shanghai Key Lab Green Chem & Chem Proc, SCME, 3663 North Zhongshan Rd, Shanghai, Peoples R China

年份：2017

卷号：842

起止页码：54

外文期刊名：JOURNAL OF ORGANOMETALLIC CHEMISTRY

收录：;EI(收录号：20171903657982);WOS:【SCI-EXPANDED(收录号:WOS:000403517200007)，CCR-EXPANDED(收录号:WOS:000403517200007)】；

基金：We are grateful for financial support provided by the National Natural Science Foundation of China (21472041) and National Key Technology R&D Program, the Ministry of Science and Technology of China (2015BAK44B00).

语种：英文

外文关键词：Cross-coupling; Diarylborinate; O, N-Chelate; Palladium; N-Heterocyclic carbene

摘要：A series of O, N-chelated diarylborinates have been prepared and tested as arylboron counterpart alternative to oxygen-labile diarylborinic acids in palladium catalyzed Suzuki coupling of aryl chlorides. 3-Dimethylaminopropyl diarylborinates (B-5a), featuring a six-membered O, N-chelated boron ring that was confirmed by single crystal X-ray diffraction, displayed a delicately balanced stability and reactivity. Their cross-coupling with structurally various aryl chlorides could be effected as efficiently as that of the parent diarylborinic acids by using 0.1 similar to 1mol% Pd(OAc)(2)/lPr/P(OPh)(3) as catalyst system, to provide the corresponding biaryls in good to excellent yields. (C) 2017 Elsevier B.V. All rights reserved.