文献类型：期刊文献

英文题名：LiHMDS-Promoted Palladium-Catalyzed Sonogashira Cross-Coupling of Aryl Fluorides with Terminal Alkynes

作者：He, Jingjing[1];Yang, Kang[1];Zhao, Jianhong[1];Cao, Song[1]

机构：[1]ECUST, Sch Pharm, Shanghai 200237, Peoples R China

年份：2019

卷号：21

期号：23

起止页码：9714

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000502163300090)，CCR-EXPANDED(收录号:WOS:000502163300090)】；

基金：We are grateful for financial support from the Joint Center of "ECUST-ZHONGXI SUNVE" for Green Pharmceutical Research & Development and National Key Research and Development Program of China (No. 2017YFD0200505).

语种：英文

摘要：A highly efficient Pd-catalyzed Sonogashira coupling of various aryl fluorides with terminal alkynes in the presence of LiHMDS was developed. Both unreactive electron-rich fluoroarenes and electron-poor fluoroarenes proceeded smoothly and afforded the corresponding internal alkynes in moderate to excellent yields.