文献类型：期刊文献

英文题名：Palladium-catalyzed cyclization of vinyl iodide-tethered allensulfonamide

作者：Xie, Zheng[1];Wu, Pan[1];Cai, Liangzhen[1];Tong, Xiaofeng[1]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

年份：2014

卷号：55

期号：13

起止页码：2160

外文期刊名：TETRAHEDRON LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000333792000029)，CCR-EXPANDED(收录号:WOS:000333792000029)】；

基金：We thank NSFC (No. 21002025 and 21272066), the Fundamental Research Funds for the Central Universities, Fok Ying-Tong Education Foundation for Young Teachers in the Higher Education Institutions of China (131011) and NCET (No. 12-0851) for funding this research.

语种：英文

外文关键词：Palladium catalysis; Allensulfonamide; Cyclization; N,O-acetal

摘要：This Letter describes a palladium-catalyzed cyclization of vinyl iodide-tethered allensulfonamide in the presence of alkylol, which provides a facile access to 2-alkoxy-3-methylene-tetrahydropyridine. The asymmetric version of this reaction has also been preliminarily realized with up to 81% enantioselectivity when chiral bisphosphine ligands were used. (C) 2014 Elsevier Ltd. All rights reserved.