文献类型：期刊文献

英文题名：A NIR luminescent copolymer based on platinum porphyrin as high permeable dissolved oxygen sensor for microbioreactors

作者：Jin, Pengwei[1,2];Chu, Ju[1,2];Miao, Yu[1,2];Tan, Jun[1,2];Zhang, Siliang[1,2];Zhu, Weihong[1,2]

机构：[1]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2013

卷号：59

期号：8

起止页码：2743

外文期刊名：AICHE JOURNAL

收录：;EI(收录号：20133116556216);WOS:【SCI-EXPANDED(收录号:WOS:000321960400004)】；

基金：The authors thank NSFC/China, National 973 Program (2013CB733700), the Oriental Scholarship, the Fundamental Research Funds for the Central Universities (WK1013002), National Major Scientific Technological Special Project (2012YQ15008709), the doctoral program of higher education of specialized research fund (20110074110015), and the Open Funding Project of the State Key Laboratory of Bioreactor Engineering for providing financial support to this project.

语种：英文

外文关键词：dissolved oxygen sensor; copolymer; platinum porphyrin; microbioreactor

摘要：Microbioreactors with multioptical sensors have become increasingly important because of their small working volumes, high degree of parallelization and the available robotics. A novel hydrophobic luminescent copolymer P(Pt-TPP-TFEMA) along with reference P(Pt-TPP-EMA) containing the pendant group of 5,10,15,20-tetraphenylporphyrin (TPP) moiety as low-cost dissolved oxygen (DO) chemosensor film for high-throughput microbioreactors is designed. Its sensor film exhibits fast response to DO with good stability and fatigue resistance, being capable of applying as a low-cost DO indicator for high-throughput bioprocess measurement. Results show that the quenching response of DO increases with the enhancement in the copolymeric hydrophobicity using the presented hybrid fluorinated ethyl methacrylate. Furthermore, the long emission band at 650 nm of chromophore TPP with large Stoke's shift about 250 nm brings several advantages, such as low scattering, deep penetration, and minimal interferences of absorption and fluorescence from the fermentation system, which shows high-promising application in bioprocess monitoring. (c) 2013 American Institute of Chemical Engineers AIChE J, 59: 2743-2752, 2013