文献类型：期刊文献

英文题名：meta-Substituted Diaryliodonium Salts Enabled Aryne 1,2,4′-Trifunctionalization

作者：Chu, Lifeng[1,2,3];Jiang, Junjie[1,2,3];Wang, Limin[1,2,3];Han, Jianwei[1,2,3]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Dept Fine Chem, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2025

卷号：27

期号：36

起止页码：10204

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001563238300001)】；

基金：This work was supported by the National Natural Science Foundation of China (NSFC 22478117). The authors thank the Research Center of Analysis and Test of East China University of Science and Technology for the help with the characterization and Professors Zhen-Jiang Xu and Hao-Yang Wang from SIOC, CAS, for helpful discussions and instrumental analysis.

语种：英文

摘要：A novel 1,2,4 '-trifunctionalization of arynes was accomplished using meta-substituted diaryliodonium salts through a unique [5,5]-sigmatropic shift followed by a thia-Fries rearrangement. This cascade transformation enables the sequential formation of both C-N and C-S bonds, while also achieving the synthetically challenging para-selective C-C bond on the non-aryne aromatic ring.