文献类型：期刊文献

英文题名：One-Pot Synthesis of Trifluoromethyl-Containing Pyrazoles via Sequential Yb(PFO)₃-Catalyzed Three-Component Reaction and IBX-Mediated Oxidation

作者：Shen, Li[1];Zhang, Jian[1];Cao, Song[1,2];Yu, Jinlong[1];Liu, Nianjin[1];Wu, Jingjing[1];Qian, Xuhong[1]

机构：[1]E China Univ Sci & Technol, Ctr Fluorine Chem Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

年份：2008

期号：19

起止页码：3058

外文期刊名：SYNLETT

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000262108300029)，CCR-EXPANDED(收录号:WOS:000262108300029)】；

基金：Financially supports from the National High Technology Research and Development Program of China (863 Program, 2006AA10A201), the Shanghai Foundation of Science of Technology (073919107), Shanghai Leading Academic Discipline Project (13507), National Key Project for Basic Research (2003CB114405), and the Shanghai Education Commission are kindly acknowledged.

语种：英文

外文关键词：trifluoromethyl-containing pyrazole; IBX; Yb(PFO)(3); three-component synthesis

摘要：Fourteen trifluoromethyl-containing fully substituted pyrazoles were synthesized via Yb(PFO)(3)-catalyzed three-component condensations of aromatic hydrazines, aldehydes, and ethyl trifluoroacetoacetate, followed by IBX-mediated oxidation of pyrazolines. A possible mechanism is suggested.