文献类型：期刊文献

中文题名：Enantioselective reduction of acetophenone analogues using carrot and celeriac enzymes system

英文题名：Enantioselective reduction of acetophenone analogues using carrot and celeriac enzymes system

作者：Liu, Xiang[1];Pan, Zheng Guang[1];Xu, Jian He[2];Li, He Xing[3]

机构：[1]Jiangnan Univ, Sch Chem & Mat Engn, Wuxi 214122, Peoples R China;[2]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[3]Shanghai Normal Univ, Dept Chem, Shanghai 200234, Peoples R China

年份：2010

卷号：21

期号：3

起止页码：305

中文期刊名：Chinese Chemical Letters

外文期刊名：CHINESE CHEMICAL LETTERS

收录：CSTPCD;;Scopus;WOS:【SCI-EXPANDED(收录号:WOS:000277378700015)】；CSCD:【CSCD2011_2012】；PubMed;

基金：This research was financially supported by the National Natural Science Foundation of China (No. 20672037), and the National Special Fund for State Key Laboratory of Bioreactor Engineering (No. 2060204).

语种：英文

中文关键词：Enantioselective reduction; Acetophenone analogues; Plant cells; Biocatalysis;

外文关键词：Enantioselective reduction; Acetophenone analogues; Plant cells; Biocatalysis

摘要：The enantioselective reduction of acetophenone analogues catalyzed by carrot and celeriac was performed in moderate conversions and excellent enantiomeric excesses.The steric factors and electronic effects of the substituents at the aromatic ring were found to significantly affect the efficiency of the enantioselective reduction of acetophenone analogues,while they had a little effect on the enantioselectivity of acetophenone analogues reduction.It was also found that the conversions of acetophenone analogu...
The enantioselective reduction of acetophenone analogues catalyzed by carrot and celeriac was performed in moderate conversions and excellent enantiomeric excesses. The steric factors and electronic effects of the substituents at the aromatic ring were found to significantly affect the efficiency of the enantioselective reduction of acetophenone analogues, while they had a little effect on the enantioselectivity of acetophenone analogues reduction. It was also found that the conversions of acetophenone analogues reduction at 33 degrees C by means of both biocatalysts were three times as great as those at room temperature. (C) 2009 Xiang Liu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.