文献类型：期刊文献

英文题名：An efficient and practical method for the synthesis of 1-(2,6-difluorobenzoyl)-3-(2-alkyl-3-oxopyridazin-4-yl)ureas as potential chitin synthesis inhibitors

作者：Cao, Song; Lu, De-Li; Zhao, Chuan-Meng; Li, -Na Li; Huang, Qing-Chun; Qian, Xu-Hong

机构：[1]E China Univ Sci & Technol, Inst Pesticides & Pharmaceut, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

年份：2006

卷号：137

期号：6

起止页码：779

外文期刊名：MONATSHEFTE FUR CHEMIE

收录：;EI(收录号：20242616560611);WOS:【SCI-EXPANDED(收录号:WOS:000239791700009)】；

语种：英文

外文关键词：bioorganic chemistry; heterocycles; microwave; insecticidal activity

摘要：A mild and efficient method for the synthesis of 4-amino-3(2H)-pyridazinones from their corresponding 4,5-dichloropyridazinones under microwave-assisted conditions is described. A series of novel chitin synthesis inhibitors, benzoylphenylureas containing the 3(2H)-pyridazinone, were synthesized. The biological activity of these target compounds was evaluated.