文献类型：期刊文献

英文题名：Helical Toroids Self-Assembled from a Binary System of Polypeptide Homopolymer and its Block Copolymer

作者：Xu, Pengfei[1];Gao, Liang[1];Cai, Chunhua[1];Lin, Jiaping[1];Wang, Liquan[1];Tian, Xiaohui[1]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Adv Polymer Mat, Sch Mat Sci & Engn, Key Lab Ultrafine Mat,Minist Educ, Shanghai 200237, Peoples R China

年份：2020

卷号：59

期号：34

起止页码：14281

外文期刊名：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

收录：;EI(收录号：20202708892505);WOS:【SCI-EXPANDED(收录号:WOS:000544387500001)】；

基金：This work was supported by the National Natural Science Foundation of China (51833003, 51621002, 21975073, and 51573049).

语种：英文

外文关键词：helices; hierarchical assembly; polypeptides; theoretical simulation; toroids

摘要：Toroids and helices are fundamental geometrical structures in nature. Polymers can self-assemble into various nanostructures, including both toroids and helices; however, nanostructures combining toroidal and helical morphologies (that is, helical toroids) are rarely observed. A binary system is reported containing polypeptide homopolymer and its block copolymer, which can hierarchically self-assemble into uniform helical nanotoroids in solution. The formation of the helical toroids is a successive two-step process. First, the homopolymers aggregate into fibrils and convolve into toroids, thereby resembling the toroidal condensation of deoxyribonucleic acid (DNA) chains. Second, the block copolymers self-assemble on the homopolymer toroids and result in helical surface patterns. Additionally, the chirality of the surface helical patterns can be varied by the chirality of the polypeptide block copolymers.