文献类型：期刊文献

英文题名：Bioactivity and biocompatibility of Na2O-K2O-CaO-MgO- SrO-B2O3-P2O5 borophosphate glass

作者：Zheng, Kai[1]; Yang, Shengbing[1]; Liang, Wen[1]; Rüssel, Christian[1,2]

机构：[1] Research Institute of Biomaterials, School of Materials Science and Engineering, East China University of Science and Technology, China; [2] Otto-Schott-Institut, Universit?t Jena, Jena, Germany

年份：2011

卷号：335-336

起止页码：1250

外文期刊名：Advanced Materials Research

收录：EI(收录号：20114014400594)

语种：英文

外文关键词：Scaffolds - Bioactivity - Hydroxyapatite - Sodium compounds - Viscosity measurement - Magnesia - Strontium compounds - Differential thermal analysis - Scaffolds (biology) - Tensile strength

摘要：A novel Na2O-K2O-CaO-MgO-SrO-B2O 3-P2O5 borophosphate glass is prepared by melting method. The thermal properties have been examined by differential thermal analysis (DTA) and viscosity measurement. The bioactivity of the glass is measured via soaking the glass in the SBF solution at 37 °C for different time. The reaction of the glass in the SBF solution is characterized by XRD, FTIR and SEM. The results indicate that the carbonate hydroxyapatite deposit on the glass in less than 7 days. Cell attachment, spreading and proliferation on the glass is determined by MTT [3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide] assay method using Human osteosarcoma MG-63 cells. The borophosphate glass fiber is also drawn and the tensile strength is measured. The results suggest the borophosphate glass has a good potential to be a scaffold material for bone tissue engineering. ? (2011) Trans Tech Publications.