文献类型：期刊文献

中文题名：Copper-catalyzed direct oxidation and N-arylation of benzylamines with diaryliodonium salts

英文题名：Copper-catalyzed direct oxidation and N-arylation of benzylamines with diaryliodonium salts

作者：Liu Xin;Mao Dan;Wu ShengYing;Yu JianJun;Hong Gang;Zhao Qiao;Wang LiMin[1]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China; E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2014

卷号：57

期号：8

起止页码：1132

中文期刊名：Science China Chemistry

外文期刊名：SCIENCE CHINA-CHEMISTRY

收录：;EI(收录号：20143318073459);Scopus;WOS:【SCI-EXPANDED(收录号:WOS:000340084700013)，CCR-EXPANDED(收录号:WOS:000340084700013)】；PubMed;

基金：This work was financially supported by the National Nature Science Foundation of China (21272069, 20672035) and the Fundamental Research Funds for the Central Universities and Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.

语种：英文

中文关键词：copper（Ⅱ） triflate; diaryliodonium salts; N-arylated amides; oxidation

外文关键词：copper(II) triflate; diaryliodonium salts; N-arylated amides; oxidation

摘要：An efficient approach for the synthesis of N-arylated amides was developed via copper(Ⅱ) triflate-catalyzed direct oxidation of(aryl)methylamines to primary arylamides by air and subsequent N-arylation by diaryliodonium salts. Various substituted benzylamines could be applied in the reaction, providing a series of N-arylated amides in moderate to good yields. This method showed convenient, practical, and environment friendly advantages.
An efficient approach for the synthesis of N-arylated amides was developed via copper(II) triflate-catalyzed direct oxidation of (aryl)methylamines to primary arylamides by air and subsequent N-arylation by diaryliodonium salts. Various substituted benzylamines could be applied in the reaction, providing a series of N-arylated amides in moderate to good yields. This method showed convenient, practical, and environment friendly advantages.