文献类型：期刊文献

中文题名：由2,3-二氯硝基苯合成2,3,4-三氟硝基苯

英文题名：Synthesis of 2,3,4 Trifluoronitrobenzene from 2,3 Dichloronitrobenzene

作者：朱志华[1];徐佩若[1];严之光[1];张明[2]

机构：[1]华东理工大学化学工程系;[2]中国科学院上海有机化学研究所

年份：1998

卷号：24

期号：6

起止页码：639

中文期刊名：华东理工大学学报（自然科学版）

外文期刊名：Journal of East China University of Science and Technology

收录：CSTPCD;;国家哲学社会科学学术期刊数据库;Scopus;北大核心:【北大核心1996】；CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：三氟硝基苯;氯化;硝化;氟化;合成;三氟硝基苯

外文关键词：trifluoronitrobenzene; synthesis; fluorination; chlorination; nitration

摘要：提出了一种以２，３－二氯硝基苯为原料，经氟化、高温氯化、硝化、再氟化反应合成２，３，４－三氟硝基苯的新工艺路线。探索了各步反应的工艺条件，对其中的关键步骤氟化反应，使用相转移催化剂取得较好的效果，反应收率比溶剂法提高１０％左右。实验表明，该合成路线具有原料成本低，反应条件缓和，操作方便等优点。
A method is given for synthesis of 2,3,4 trifluoronitrobenzene from 2,3 dichloronitrobenzene by fluorination, chlorination, nitration, etc. The suitable technological conditions were investigated for each steps. In order to increase the yield of fluorination which was the key step, some phase transfer catalysts were used and researched. The result showed that the yield of fluorination was increased about 10% more in phase transfer catalysts than in solvents. As compared with the other methods for preparing 2,3,4 trifluoronitrobenzene, this synthesis route has many advantages with respect to low costs, mild conditions, easy operations, etc. It has been proved that this is a new practical synthesis method in technology and economy.