文献类型：期刊文献

英文题名：Synthesis of 2,5-epoxy-1,4-benzoxazepines via rhodium(II)-catalyzed reaction of 1-tosyl-1,2,3-triazoles and salicylaldehydes

作者：Meng, Jiang[1];Ding, Xiangfeng[1];Yu, Xingxin[1];Deng, Wei-Ping[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China

年份：2016

卷号：72

期号：1

起止页码：176

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000367276300018)，CCR-EXPANDED(收录号:WOS:000367276300018)】；

基金：This work is supported by the National Natural Science Foundation of China (No. 21402049).

语种：英文

外文关键词：1-Tosyl-1,2,3-triazoles; alpha-Imino carbenes; Zwitterionic intermediates; Polycyclic ethers; Azaheterocycles

摘要：The alpha-imino carbenes generating from 1-tosyl-1,2,3-triazoles have exhibited unique reactivities. A novel and efficient route for the construction of oxa-bridged 2,5-epoxy-1,4-benzoxazepines through a rhodium(II)-catalyzed tandem process of triazoles and salicylaldehydes has been developed. The oxazoles are obtained when 2-methanesulfonamidyl benzaldehyde is used instead of salicylaldehydes. (C) 2015 Elsevier Ltd. All rights reserved.