文献类型：期刊文献

中文题名：原花青素体外清除自由基活性的研究

英文题名：Scavenging Activity of Procyanidins on Free Radicals

作者：余莹[1];粟武[1];魏东芝[1]

机构：[1]华东理工大学生物化学研究所,上海200237

年份：2002

卷号：28

期号：3

起止页码：318

中文期刊名：华东理工大学学报（自然科学版）

外文期刊名：Journal of East China University of Science and Technology

收录：CSTPCD;;Scopus;北大核心:【北大核心2000】；CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：原花青素;自由基;活性;葡萄籽;DPPH;抗氧剂;植物药

外文关键词：grape procyanidins; free radical; DPPH; 2 deoxyribose; antioxidant

摘要：从葡萄籽中提取高纯度的原花青素 ,测得其对稳定自由基 1 ,1 -联苯 -β-苦基偕腙肼( DPPH)的半数抑制浓度 ( EC50 )为 44mg/L ;又利用 2 -脱氧 - D-核糖法产生· OH,在原花青素浓度为 1 0 g/L时可清除该体系中 80 %的· OH。
The purified procyanidins were obtained from grape seeds and its scavenging activity on DPPH and hydroxyl radicals was determined. The results showed that the 50% scavenging concentration ( EC 50 ) was 44mg/L in the DPPH and 80 percentage hydroxyl radicals was scavenged when the concentration was 10g/L. These results suggested that procyanidins would be a effective natural free radical scavenger.