文献类型：期刊文献

英文题名：Br?nsted acid-catalyzed aza-Mannich reaction of N-Boc aminals: access to multifunctional rhodanine/hydantoin derivatives

作者：Zou, Kaihe[1]; Wu, Xin-Yan[1]; Ye, Jinxing[2,3]

机构：[1] Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai, 200237, China; [2] Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China; [3] Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China

年份：2017

卷号：43

期号：8

起止页码：4503

外文期刊名：Research on Chemical Intermediates

收录：EI(收录号：20170803365905)

语种：英文

摘要：An effective aza-Mannich reaction between olefinic rhodanines/hydantoins and N-Boc aminals catalyzed by Br?nsted acid has been developed. Multifunctional rhodanine/hydantoin derivatives were obtained in 71–86% yields and an up to 95/5 Z/E ratio under mild conditions. ? 2017, Springer Science+Business Media Dordrecht.