文献类型：期刊文献

中文题名：Computational fluid dynamics simulation and experimental study on mixing performance of a three-dimensional circular cyclone-type microreactor

作者：Shiyu Hou[1];Maolin Sun[2];Liming Cao[3];Chaoming Liang[2];Jiaxin Yang[2];Xinggui Zhou[1];Jinxing Ye[2,3];Ruihua Cheng[1,2]

机构：[1]School of Chemical Engineering,East China University of Science and Technology,Shanghai 200237,China;[2]School of Biomedical and Pharmaceutical Sciences,Guangdong University of Technology,Guangzhou 510006,China;[3]School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China

年份：2024

卷号：35

期号：4

起止页码：382

中文期刊名：Chinese Chemical Letters

外文期刊名：中国化学快报(英文版)

收录：CSTPCD;;Scopus;CSCD:【CSCD2023_2024】；PubMed;

语种：英文

中文关键词：Microfluidics;Passive microreactor;CFD simulation;Extraction;Liquid-liquid biphase reaction

摘要：Microchannels enable the fast and efficient mixing of multiphase fluids.In this study,a millimeter-scale three-dimensional(3D)circular cyclone-type microreactor was designed for the mixing.The flow characteristics and mixing intensity were simulated by computational fluid dynamics simulations at a flow rate range of 12–96 m L/min using a water/ethyl acetate system.In the 3D variable-diameter structure,the microreactor induced paired opposite vortices and abruptly changed the local pressure to achieve a stable turbulent effect within the theoretical range of laminar flow.Tracer injection simulations indicated that sufficient mixing units successfully promote fluid dispersion.Diazo-coupling experiments showed a segregation index of X_S=0.00,039 within a residence time of 9 s.Extraction experiments on the nbutanol/succinic acid/water system showed that the 3D circular cyclone-type microreactor achieved 100%extraction efficiency(E)in 4.25 s,and the overall volume mass transfer coefficient(K_La)reached 0.05–1.5s^(-1)in 12–96 m L/min.The isolated yield of the phase transfer alkylation and oxidation reactions in the 3D circular cyclone-type microreactor achieved 99%within 36 s,which was superior to the coil microreactor and batch reactor.