文献类型：期刊文献

英文题名：Antibacterial HPL-DOSS surface coating for commercial plastics

作者：Chen, Guohao[1,2];Liu, Xiao[2];Zhang, Rui[1,3];Han, Miaomiao[2,4];Ji, Shengxiang[2,4]

机构：[1]East China Univ Sci & Technol, Shanghai, Peoples R China;[2]Chinese Acad Sci, Changchun Inst Appl Chem, Key Lab Polymer Ecomat, Jilin, Peoples R China;[3]East China Univ Sci & Technol, Shanghai 200237, Peoples R China;[4]Chinese Acad Sci, Changchun Inst Appl Chem, Key Lab Polymer Ecomat, 5625 Renmin St, Changchun 130022, Jilin, Peoples R China

年份：2023

卷号：70

期号：11

起止页码：1986

外文期刊名：JOURNAL OF THE CHINESE CHEMICAL SOCIETY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001066391400001)】；

基金：Jilin Province Science Technology Development Plan Project, Grant/Award Number: 20230508114RC; National Key Research and Development Program of China, Grant/Award Numbers: 2022YFC2603500, 2022YFC2603504

语种：英文

外文关键词：antibacterial coating; antifouling; bactericidal; hyperbranched polylysine

摘要：Bacterial colonization and biofilm formation on the surface of materials can lead to serious bacterial infections and are highly detrimental to our health. Here, we prepared a water-insoluble HPL-DOSS complex by compounding hyperbranched polylysine (HPL) with docusate sodium salt (DOSS) and coated HPL-DOSS onto the surfaces of the commercial polypropylene (PP) and thermoplastic polyurethane (TPU) plastics to afford antibacterial PP-HD and TPU-HD plastics. PP-HD and TPU-HD showed excellent antibacterial activities against both Escherichia coli and MRSA. In addition, the bacterial residues on the PP-HD and TPU-HD surfaces were significantly reduced compared with the pristine PP and TPU surfaces, indicating that the HPL-DOSS surface coating had good anti-adhesive property against bacteria and helped to reduce the formation of biofilms. Meanwhile, both PP-HD and TPU-HD exhibited excellent biocompatibility, indicating that the HPL-DOSS complex could be used as a safe antimicrobial coating material to reduce bacterial infections on plastic surfaces.