文献类型：期刊文献

英文题名：Simple Cyclohexanediamine-Derived Primary Amine Thiourea Catalyzed Highly Enantioselective Conjugate Addition of Nitroalkanes to Enones

作者：Mei, Kui[1];Jin, Mei[1];Zhang, Shilei[1];Li, Ping[1];Liu, Wenjing[1];Chen, Xiaobei[1];Xue, Fei[1];Duan, Wenhu[1,2];Wang, Wei[1,3]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Dept Pharmaceut Sci, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Grad Sch, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;[3]Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA

年份：2009

卷号：11

期号：13

起止页码：2864

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000267400100038)，CCR-EXPANDED(收录号:WOS:000267400100038)】；

基金：We are grateful for the financial Support from School of Pharmacy, East China University of Science, the China III Project (Grant No. B07023), the National Science Foundation of China (Nos. 03772648 and 30721005), and the Chinese National Programs for High Technology Research and Development (Nos. 2006AA020602 and 2007AA02Z147).

语种：英文

摘要：A highly enantioselective conjugate addition of nitroalkanes to enones has been developed. The process is efficiently catalyzed by a simple chiral cyclohexanediamine-derived primary amine thiourea with a broad substrate scope.