文献类型：期刊文献

英文题名：Synthesis of symmetric 1,4-diamino-2-butynes via a Cu(I)-catalyzed one-pot A3-coupling/decarboxylative coupling of a propiolic acid, an aldehyde, and an amine

作者：Feng, Huangdi[1,2]; Ermolat'ev, Denis S.[1]; Song, Gonghua[2]; Van Der Eycken, Erik V.[1]

机构：[1] Laboratory for Organic and Microwave-Assisted Chemistry [LOMAC], Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium; [2] Shanghai Key Laboratory of Chemical Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China

年份：2012

卷号：77

期号：11

起止页码：5149

外文期刊名：Journal of Organic Chemistry

收录：EI(收录号：20122315100510)

语种：英文

外文关键词：Catalysis - Copper compounds

摘要：A novel microwave-assisted approach for the one-pot Cu(I)-catalyzed A 3-coupling/decarboxylative coupling (PA2-coupling) of a propiolic acid, an aldehyde, and an amine, resulting in the formation of diversely substituted 1,4-diamino-2-butynes,is described. It is noteworthy that this new multicomponent coupling provides an efficient access to introduce alkyl and aryl group at the 1,4-position of the 1,4-diamino-2-butynes. ? 2012 American Chemical Society.