文献类型：期刊文献

英文题名：Palladium-catalyzed 1,4-addition of secondary alkylphenylphosphines to α,β-unsaturated carbonyl compounds for the synthesis of phosphorus- and carbon-stereogenic compounds

作者：Li, Chun[2];Bian, Qing-Long[2];Xu, Sheng[2];Duan, We-Liang[1]

机构：[1]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China;[2]E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2014

卷号：1

期号：5

起止页码：541

外文期刊名：ORGANIC CHEMISTRY FRONTIERS

收录：;EI(收录号：20184806135763);WOS:【SCI-EXPANDED(收录号:WOS:000364426500014)】；

基金：We thank the National Basic Research Program of China (973 Program 2010CB833300), the NSFC (20902099, 21172238), and SIOC for funding this work.

语种：英文

外文关键词：Catalysis - Palladium compounds - Carbonyl compounds - Unsaturated compounds - Phosphorus compounds

摘要：Highly stereoselective 1,4-addition of alkylphenylphosphines to 11,1i-unsaturated carbonyl compounds catalyzed by PCP or NCN pincer Pd complexes is described to synthesize chiral phosphorus compounds bearing both P- and C-stereogenic centers with good to excellent enantioselectivity (up to 99.6% ee).