文献类型：期刊文献

英文题名：Enriched separation of protopanaxatriol ginsenosides, malonyl ginsenosides and protopanaxadiol ginsenosides from Panax ginseng using macroporous resins

作者：Mi, Jianing[2];Zhang, Min[1];Ren, Guixiang[1];Zhang, Hongyang[2];Wang, Yuerong[2];Hu, Ping[2]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Modern Engn Ctr Tradit Chinese Med, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

年份：2012

卷号：113

期号：4

起止页码：577

外文期刊名：JOURNAL OF FOOD ENGINEERING

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000310043600011)】；

基金：This research was financially funded by the National Natural Science Foundation of China (No. 21006023), the Fundamental Research Funds for the Central Universities, and Shanghai-Unilever Research & Development Fund (No. 08520750300). The authors would like to thank Ms. Ting Lu her technical support during experimental work.

语种：英文

外文关键词：Enriched separation; Ginsenosides; Malonyl ginsenosides; Macroporous resin

摘要：This study developed a method for enriched separation of protopanaxatriol ginsenosides, malonyl ginsenosides and protopanaxadiol ginsenosides from Panax ginseng. The method began with targets extraction from herbal material, followed by HPD300 resins separation, then extracted by water-statured n-butanol. In the product achieved, protopanaxatriol ginsenosides were 24.4% pure with 70.9% recovery, malonyl ginsenosides were 33.4% pure with 23.3% recovery, and protopanaxadiol ginsenosides as well as Ro were 31.3% pure with 56.8% recovery. The adsorption test data on HPD300 resins fit the Langmuir model well. Moreover, the pseudo-first-order kinetic model showed the best correlation with the adsorption results. These findings indicate that the combination of HPD300 resin chromatography and water-statured n-butanol extraction effectively separates and enriches ginsenosides from P. ginseng. (C) 2012 Elsevier Ltd. All rights reserved.