文献类型：期刊文献

英文题名：Enhanced photodynamic therapy through supramolecular photosensitizers with an adamantyl-functionalized porphyrin and a cyclodextrin dimer

作者：Xia, Lei[1];Wu, Jian[1];Huang, Baoxuan[1];Gao, Yun[1];Tian, Jia[1];Zhang, Weian[1]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2020

卷号：56

期号：75

起止页码：11134

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;EI(收录号：20204009288556);WOS:【SCI-EXPANDED(收录号:WOS:000571593700030)】；

基金：The authors acknowledge the financial support from the National Natural Science Foundation of China (No. 21875063 and 51803058) and the Fundamental Research Funds for the Central Universities (No. 222201814018).

语种：英文

外文关键词：Porphyrins - Cyclodextrins - Photodynamic therapy - Supramolecular chemistry

摘要：A supramolecular photosensitizer was constructed using a tetra-adamantane-functionalized porphyrin and a dimer of permethyl-beta-cyclodextrin through host-guest interaction and self-assembly. The porphyrin/cyclodextrin alternating structure of supramolecular photosensitizers not only enhances the water solubility of the photosensitizers, but also effectively inhibits the aggregation-induced quenching of porphyrin photosensitizers.