文献类型：期刊文献

英文题名：Two New Antifungal Cyclic Lipopeptides from Bacillus marinus B-9987

作者：Zhang, Dao-Jing[1];Liu, Rong-Feng[1];Li, Yuan-Guang[1];Tao, Li-Ming[2];Tian, Li[3]

机构：[1]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Pharmaceut Coll, Shanghai 200237, Peoples R China;[3]State Ocean Adm, Inst Oceanog 1, Qingdao 266061, Peoples R China

年份：2010

卷号：58

期号：12

起止页码：1630

外文期刊名：CHEMICAL & PHARMACEUTICAL BULLETIN

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000284860800015)】；

基金：This work was financially supported by the High-Tech Program (863 Program) of China (2007AA091507, 2007AA09Z435 and 2008AA09Z407), and the National Special Fund for State Key Laboratory of Bioreactor Engineering, Grant No 2060204 We gratefully thank Courtni Newsome (Department of Surgery, Brown University School of Medicine-Rhode Island Hospital, Providence, RI, 02903, U S A) for his assistance with English editing

语种：英文

外文关键词：Bacillus marinus; cyclic lipopeptide; antifungal activity; maribasin A; maribasin B

摘要：Two new cyclic lipopeptides maribasins A (1) and B (2) were isolated from the fermentation broth of the marine microorganism Bacillus marinas B-9987 Isolated from Suaeda salsa in Bohai coastline of P. R. China. Both structures were established to be cyclo (D-Pro-L-Gln-L-Asn-L-Ser-D-Asn(1)-D-Tyr-D-Asn(2)-D-beta-aminoisopentadecanoic acid) (1) and cyclo (D-Pro-L-Gln-L-Asn-L-Ser-D-Asn(1)-D-Tyr-D-Asn(2)-D-beta-aminoanteisopentadecanoic acid) (2) by spectroscopic analysis and exhibited broad-spectrum activity against phytopathogens by the antifungal bioassay.