文献类型：期刊文献

英文题名：Magnetic biochar derived from penicillin fermentation residue for efficient penicillin G sodium adsorption: kinetics, degradation mechanism, and simulations

作者：Zhang, Sinan[1,2,3];Wang, Zejian[3];Huang, Sheng[1,2];Deng, Xuheng[4];Wu, Jiequn[5];Wu, Shiyong[1,2]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Resource Utilizat Carbon Containing W, Minist Educ, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, State Key Lab Coal Liquificat Gasificat & Utilizat, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Dept Biotechnol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[4]Yili Chuanning Biotechnol Co, Xinjiang 832003, Peoples R China;[5]Zhejiang Univ Technol, Hangzhou 310014, Peoples R China

年份：2025

卷号：435

外文期刊名：BIORESOURCE TECHNOLOGY

收录：;EI(收录号：20252618686414);WOS:【SCI-EXPANDED(收录号:WOS:001525424300001)】；

基金：This work was supported by the financial support of research projects from the National Key R & D Program of China (No. 2021YFC2101000) , Shanghai Scientific and Technological Innovation Action Plans-Scien-tific Instrument Development, China (grant No. 21142201300, 22142201000) , National Natural Science Foundation of China (No. 32071471) .

语种：英文

外文关键词：Antibiotic fermentation residue biochar; Solid waste; Organic pollutants; Removal mechanism; DFT calculation

摘要：The escalating environmental contamination from penicillin G sodium (PGNa) misuse poses significant threats to ecosystem integrity and public health, necessitating advanced remediation strategies. In this study, porous magnetic biochar (SAMB) was derived from penicillin fermentation residues through coupled covalent precipitation and acid-alkali modification (98.3 % PGNa removal within 2 h). Mechanistic investigations combining density functional theory and liquid chromatography-mass spectrometry revealed that PGNa was degraded by beta-lactam ring cleavage followed by decarboxylation, decarbonylation, demethylation, and deamidation. Regeneration experiments showed that SAMB still maintained 33.8 % PGNa removal efficiency after five cycles. In addition, ecotoxicological assessment using the ECOlogical Structure Activity Relationship predictive model confirmed substantially reduced aquatic toxicity of resultant intermediates. Conversion of penicillin residue into magnetic biochar SAMB simultaneously achieves waste resource utilization and effective PGNa removal, providing dual environmental benefits for antibiotic pollution control and circular economy practices.