文献类型：期刊文献

英文题名：Pneumocandin B0-imprinted Polymer Using Surface-imprinting Technique for Efficient Purification of Crude Product

作者：Zhang, Lu[1];Zhang, Hua[1];Li, Le[1];Zuo, Peng[2];Zhao, Feilang[3];Liu, Manhua[1];Ye, Bang-Ce[2,4];Li, Yingchun[1,3,4]

机构：[1]Shihezi Univ, Sch Pharm, Minist Educ, Key Lab Xinjiang Phytomed Resources, Shihezi 832000, Peoples R China;[2]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[3]Jiangsu Devote Instrumental Sci & Technol Co Ltd, Huaian 223001, Jiangsu, Peoples R China;[4]Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832003, Peoples R China

年份：2016

卷号：32

期号：9

起止页码：923

外文期刊名：ANALYTICAL SCIENCES

收录：;EI(收录号：20191506755364);WOS:【SCI-EXPANDED(收录号:WOS:000384277400001)】；

基金：This project was financially supported by Open Funding Project of the State Key Laboratory of Bioreactor Engineering, the Major Program for Science and Technology Development of Shihezi University (gxjs2014-zdgg04), National Natural Science Foundation of China (81260487, 81460543, 21575089), the Scientific Research Foundation for the Returned Overseas Chinese Scholars from Ministry of Human Resources and Social Security of China (RSLX201301), the Pairing Program of Shihezi University with Eminent Scholar in Elite University (SDJDZ201502) and Key Technical Innovation Project of Xinjiang Uygur Autonomous Region in 2015.

语种：英文

外文关键词：Molecularly imprinted polymer; surface molecular imprinting; pneumocandin B-0; silica gel

摘要：In this work, we prepared surface molecularly imprinted polymer (MIP) for selective recognition of pneumocandin B-0 (PNB0). Methacrylic acid (MAA) was first grafted onto silica gel particles (SiO2) in the manner of "grafting from" by using 3-methacryloxypropyl trimethoxysilane as intermedium, and then PNB0 molecules were imprinted on the surface of the obtained particles in the presence of ethylene glycol diglycidyl ether as the cross-linker. The prepared MIP-PMAA/SiO2 was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy and thermo-gravimetric analysis, which confirmed the successful grafting of MAA onto SiO2 and the grafting degree was calculated to be 12.50 wt%. The binding properties of the products were investigated and it is found that the binding process of PNB0 followed the pseudo-second-order kinetic model. The as-prepared material also displays relatively quick adsorption kinetics and decent recognition affinity toward the template over its structurally related compound.