文献类型：期刊文献

英文题名：Practical povidone iodine catalyzed transamidation from primary amides and amines

作者：Wang, Jian[1];Ren, Jiangmeng[1];Zhu, Yun-Peng[1];Sun, Xue-Qin[1];Hu, Peng -Fei[1];Mu, Xin[1];Zeng, Bu -Bing[1]

机构：[1]East China Univ Sci & Technol, Shanghia Frontiers Sci Ctr Optogenet Tech Cell Met, Sch Pharm, 130 Meilong Rd, Shanghai, Peoples R China

年份：2023

卷号：116

外文期刊名：TETRAHEDRON LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000931414500001)，CCR-EXPANDED(收录号:WOS:000931414500001)】；

基金：This work was financially supported by Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism (Shanghai Municipal Education Commission) and Natural Science Foundation of Shanghai (22ZR1416700) .

语种：英文

外文关键词：PVP-I; Transamidation; Primary amides

摘要：Non-harmful Povidone iodine (PVP-I) was applied in the transamidation to gain N-substituted amides from various primary amides and amines. Diverse aromatic, heterocyclic and aliphatic primary amides/amines were applied in our developed method and more than 45 N-substituted amides were obtained with excellent yields in most cases. Several drugs such as Melatonin and Efaproxiral were suc-cessfully acquired with a better performance than those previous reported results.(c) 2022 Elsevier Ltd. All rights reserved.