文献类型：期刊文献

中文题名：育亨宾类似物Sempervilam的全合成

英文题名：Total Synthesis of Yohimbane Analogue Sempervilam

作者：谭新刚[1];施小新[1];衣学玉[1]

机构：[1]华东理工大学药学院,上海200237

年份：2022

卷号：85

期号：6

起止页码：755

中文期刊名：化学通报

外文期刊名：Chemistry

收录：CSTPCD;;北大核心:【北大核心2020】；CSCD:【CSCD_E2021_2022】；

语种：中文

中文关键词：育亨宾类似物;Sempervilam;合成

外文关键词：Yohimbane analogue;Sempervilam;Synthesis

摘要：以庚二酸为起始原料,经过十步反应,得到目标产物育亨宾类似物Sempervilam,总收率19%。其结构经^(1)H NMR、^(13)C NMR、IR和MS表征。此法绿色环保、成本较低,适合工业化生产。
The yohimbane analogue sempervilam was prepared from heptanediacid. The total yield of the ten steps is 19%. The structures of all compounds were characterized by ^(1)H NMR,^(13)C NMR, IR and MS. The method is environmentally friendly, lower cost, and has potential for industrial production.