文献类型：期刊文献

英文题名：Protection effect of 20(S)-ginsenoside Rg₂ extracted from cultured Panax notoginseng cells on hydrogen peroxide-induced cytotoxity of human umbilical cord vein endothelial cells in vitro

作者：Xin, XJ; Zhong, JJ; Wei, DZ; Liu, JW

机构：[1]E China Univ Sci & Technol, Inst Biochem, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2005

卷号：40

期号：10

起止页码：3202

外文期刊名：PROCESS BIOCHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000231833100008)】；

语种：英文

外文关键词：20(S)-ginsenoside Rg(2); VEC-304; plasmonigen activator (PA); reactive oxygen species (ROS)

摘要：Ginseng saponins 20(S)-ginsenoside Rg(2) extracted from cultured Panax notoginseng cells in a fermenter show a protection effect on human umbilical cord vein endothelial cells (VEC-304) from H2O2-induced cell apoptosis. When 50 mu g/ml 20(S)-ginsenoside Rg(2) was present in the culture medium for 8 h, the H2O2-damaged VEC-304 cells acquired about 11-fold (p < 0.01) on the amount and about 2-fold (p < 0.05) increase in PA activity compared with those untreated cells. And the Rg(2) has a strong ability in scavenging intracellular ROS induced by H2O2. (c) 2005 Published by Elsevier Ltd.