文献类型：期刊文献

英文题名：Palladium(ii)-catalyzed enantioselective intermolecular oxidative diarylation of internal enamides

作者：Xia, Tingting;Xi, Yang;Ding, Haojie;Zhang, Yetong;Fang, Ke;Wu, Xianqing;Qu, Jingping;Chen, Yifeng[1]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem,Sch Ch, 130 Meilong Rd, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Joint Int Res Lab Precis Chem & Mol Engn, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem,Sch Ch, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2022

卷号：58

期号：66

起止页码：9282

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;EI(收录号：20223112529650);WOS:【SCI-EXPANDED(收录号:WOS:000832629400001)，CCR-EXPANDED(收录号:WOS:000832629400001)】；

基金：This work was supported by NSFC/China (22171079), Natural Science Foundation of Shanghai (21ZR1480400), Shanghai RisingStar Program (20QA1402300), Shanghai Municipal Science and Technology Major Project (Grant No. 2018SHZDZX03), the Program of Introducing Talents of Discipline to Universities (B16017) and the Fundamental Research Funds for the Central Universities (222201717003). The authors thank the Research Center of Analysis and Testing of East China University of Science and Technology for the help with NMR analysis.

语种：英文

外文关键词：Enantioselectivity - Palladium compounds

摘要：The construction of vicinal stereogenic centers via the simultaneous formation of two C-C bonds across alkenes under oxidative conditions is a stubborn challenge. Herein, we report a Pd(ii)-catalyzed highly enantioselective intermolecular oxidative 1,2-diarylation reaction of internal enamides with aryl boronic acids, enabling the expedient construction of two vicinal stereocenters with excellent diastereo-, and enantioselectivities.