文献类型：期刊文献

英文题名：Stereoselective synthesis of α-glucosides with glucosyl (Z)-Ynenoates as donors

作者：Ma, Zhi[1];Hu, Yi[1];Li, Xiaona[1];Liu, Rongkun[1];Xia, E.[1];Xu, Peng[2];Yang, You[1]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met, Shanghai Key Lab New Drug Design,Sch Pharm,Minist, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China

年份：2023

卷号：523

外文期刊名：CARBOHYDRATE RESEARCH

收录：;EI(收录号：20224513091200);WOS:【SCI-EXPANDED(收录号:WOS:000891775300009)】；

基金：Financial support from the National Natural Science Foundation of China (21871081, 22071054) , the Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism (Shanghai Municipal Education Commission) , the First-Class Discipline Construction and Characteristic Development Guidance Funds for the Central Universities (SLC13223002) , and the Shanghai Key Laboratory of New Drug Design (SKLNDD-KF-202202) is gratefully acknowledged.

语种：英文

外文关键词：Glycosylation; Glucan; Carbohydrate; Oligosaccharide; Gold

摘要：A SPhosAuNTf2-promoted DMF-modulated glycosylation approach with glycosyl (Z)-ynenoates as donors was developed for highly alpha-selective synthesis of various linkage types of alpha-glucans. The substituent groups were also found to play a significant role in the alpha-selective glucosylation reactions. The glycosylation approach was effectively applied to the stereospecific synthesis of the alpha-1,6-linked triglucoside.