详细信息

豆油对头孢菌素C发酵影响的初步研究    

Preliminary study on the effect of soybean oil on cephalosporin C fermentation

文献类型:期刊文献

中文题名:豆油对头孢菌素C发酵影响的初步研究

英文题名:Preliminary study on the effect of soybean oil on cephalosporin C fermentation

作者:郭元昕[1];李景森[1];储炬[1];庄英萍[1]

机构:[1]华东理工大学生物反应器工程国家重点实验室,上海200237

年份:2010

卷号:35

期号:10

起止页码:747

中文期刊名:中国抗生素杂志

外文期刊名:Chinese Journal of Antibiotics

收录:CSTPCD;;Scopus;北大核心:【北大核心2008】;CSCD:【CSCD2011_2012】;

语种:中文

中文关键词:豆油;头孢菌素C;脂肪酶;发酵

外文关键词:Soybean oil; Cephalosporin C; Lipase; Fermentation

摘要:本文主要考察了基础培养基添加豆油以及不同发酵时间流加豆油对头孢菌素C发酵特性的影响。实验结果表明在72h,84h,96h三个时间添加点中,以72h添加豆油为最佳;72h的豆油添加中以0.8%的添加量效果最好,其脂肪酶活比对照平均高出14.8%,放瓶效价提高6.6%。为以后进行的发酵罐实验提供了有参考价值的数据。
The effect of adding soybean oil to basal culture medium and feed oil timing on cephalosporin C fermentation characteristics were studied. The results showed that among the three feeding points (72h, 84h and 96h), 72h is the best one. It was showed that 0. 8% soybean oil feeding at 72h could increase lipase activity by 14. 8% and titer 6.6% respectively, compared to control. The results provide significant reference data for future bioreactor experiments.

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