文献类型：期刊文献

中文题名：Facile Synthesis of 4,5-Disubstituted 2H-1,2,3-Triazoles by Catalyst-free Cycloaddition between Substituted Vinyl Sulfones and Sodium Azide under Ambient Conditions

英文题名：Facile Synthesis of 4,5-Disubstituted 2H-1,2,3-Triazoles by Catalyst-free Cycloaddition between Substituted Vinyl Sulfones and Sodium Azide under Ambient Conditions

作者：Yang Jinjin[1];Yin Wei[1];Liu Renhua[1];Chu Changhu[1]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China

年份：2012

卷号：30

期号：12

起止页码：2786

中文期刊名：中国化学（英文版）

外文期刊名：CHINESE JOURNAL OF CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000312942500011)，CCR-EXPANDED(收录号:WOS:000312942500011)】；

基金：We acknowledge the financial support from the National Natural Science Foundation of China (No. 21172072), the Shanghai Natural Science Foundation (No. 11ZR1408500) and the Shanghai Committee of Science and Technology (Grant 11DZ2260600).

语种：英文

外文关键词：vinyl sulfone; sodium azide; cycloaddition; 1; 2; 3-triazole; catalyst free

摘要：A highly efficient method for readily preparing 4,5-disubstituted 2H-1,2,3-triazoles was found. Under ambient conditions, a catalyst free cycloaddition between substituted vinyl sulfones and sodium azide could be completed in a very short time. In this cycloaddition process, sulfonyl group acts as a leaving group, while its ester group was retained.