文献类型：期刊文献

英文题名：Organocatalytic Asymmetric Michael Addition/Carbon-Carbon Bond Cleavage of Trifluoromethyl α-Fluorinated gem-Diols to Nitroolefins

作者：Saidalimu, Ibrayim[1,2];Fang, Xiang[1,2];Lv, Wenwen[1,2];Yang, Xueyan[1,2];He, Xiaopeng[1,2];Zhang, Jingyuan[1,2];Wu, Fanhong[1,2,3]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Sch Chem & Mol Engn, Shanghai, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai, Peoples R China;[3]Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai, Peoples R China

年份：2013

卷号：355

期号：5

起止页码：857

外文期刊名：ADVANCED SYNTHESIS & CATALYSIS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000316808200006)，CCR-EXPANDED(收录号:WOS:000316808200006)】；

基金：We are grateful to the National Natural Science Foundation of China (Nos. 21172148, 21202044, 21202045) and Science and Technology Commission of Shanghai Municipality (No. 10540501300) for financial support.

语种：英文

外文关键词：asymmetric Michael addition; carbon-carbon bond cleavage; thiourea catalysts; trifluoroacetate release; trifluoromethyl -fluorinated gem-diols

摘要：A new organocatalytic asymmetric Michael addition reaction by cleavage of carbon-carbon bonds through a mild release of trifluoroacetate has been developed. The reported method generates the decarboxylated -nitro--fluorocarbonyl products with excellent enantioselectivies (up to 98% ee) and good diastereoselectivies (up to 20:1 dr).