文献类型：期刊文献

英文题名：A convenient synthesis of α,α′-bis(substituted benzylidene)cycloalkanones catalyzed by Yb(OTf)₃ under solvent-free conditions

作者：Wang, LM; Sheng, J; He, T; Han, JW; Fan, ZY; Qian, CT

机构：[1]E China Univ Sci & Technol, Inst Fine Chem, Adv Mat Lab, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Lab Organomet Chem, Shanghai 200032, Peoples R China

年份：2004

期号：18

起止页码：3060

外文期刊名：SYNTHESIS-STUTTGART

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000225910800019)，CCR-EXPANDED(收录号:WOS:000225910800019)】；

语种：英文

外文关键词：alpha,alpha '-bis (substituted benzylidene)cycloalkanones; crossed aldol condensation; Yb(OTf)(3); solvent-free

摘要：An array of aromatic aldehydes undergoes crossed aldol condensation with ketones in the presence of a catalytic amount of Yb(OTf)(3) under solvent-free conditions to afford the corresponding alpha,alpha'-bis(substituted benzylidene)cycloalkanones in excellent yields without occurrence of any side reactions. This method is very general, simple and environmental friendly in contrast with the existing methods, which use many classical Lewis acids. Furthermore, the catalyst can be recovered conveniently and reused efficiently without the loss of activity.