文献类型：期刊文献

英文题名：Polychromatic fluorescent sensor for hydrogen sulfate anion recognition based on molecular conformation transformation

作者：Wu, Yifan;Yang, Chuanxing;Li, Lu;Wang, Qiaochun;Zhang, Zhiyun;Su, Jianhua;Chen, Xuanying[1];Guo, Lifang[1]

机构：[1]East China Univ Sci & Technol, Frontiers Sci Ctr Materiobiol & Dynam Chem, Feringa Nobel Prize Scientist Joint Res Ctr, Key Lab Adv Mat, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Frontiers Sci Ctr Materiobiol & Dynam Chem, Feringa Nobel Prize Scientist Joint Res Ctr, Joint Int Res Lab Precis Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2025

卷号：433

外文期刊名：SENSORS AND ACTUATORS B-CHEMICAL

收录：;EI(收录号：20251018000250);WOS:【SCI-EXPANDED(收录号:WOS:001443122800001)】；

基金：We are thankful for financial support from the NSFC/China (22335004, 22474039) , National Funded Postdoctoral Researcher Program (GZC20230794) and China Postdoctoral Science Foundation (2024M750899, 2024T170272) .

语种：英文

外文关键词：Vibration-induced emission; Conformation transformation; Hydrogen sulfate anion; Polychromatic fluorescent sensor; Non-covalent interaction

摘要：Detection of hydrogen sulfate anion (HSO4-) is becoming crucial in biology, environmental sciences, and catalysis scientific fields. Herein, we demonstrate a strategy for precisely and visually detecting hydrogen sulfate anion (HSO4-) by polychromic fluorescence variations based on molecular conformation transformation in the mixed solvent of acetonitrile and water (v/v = 4:1) with the detection limit of 5.08 mu M. With the combination of a flexible skeleton of N,N'-diphenyl-dihydrodibenzo[a,c]-phenazine (DPAC) and two recognition 'claws' of triazole units, the fluorescent sensor DPAC-Tz was designed and synthesized. Depending on the non-covalent binding affinity of triazole units with hydrogen sulfate anions, the bend-to-twisted conformation evolution of DPAC moiety in the excited state was restricted, resulting in the significant fluorescent color conversion from orange to blue. The non-covalent interaction mode was investigated by 1H NMR spectroscopic analysis and density functional theory (DFT) calculations as well as IGMH analysis, and the application of DPAC-Tz on hydrogen sulfate anions was demonstrated in the living cells imaging. This study explicitly reveals the application prospect of combining flexible scaffolds with dynamic structural evolution and non-covalent intermolecular interactions for analyte sensing, thereby inspiring the exploitation of polychromatic fluorescent sensors with high selectivity and visibility in various chemical detections.