文献类型：期刊文献

英文题名：Versatile Antibacterial Materials: An Emerging Arsenal for Combatting Bacterial Pathogens

作者：Ding, Xiaokang[1];Duan, Shun[1];Ding, Xuejia[1];Liu, Runhui[2];Xu, Fu-Jian[1]

机构：[1]Beijing Univ Chem Technol, Beijing Lab Biomed Mat, Beijing Adv Innovat Ctr Soft Matter Sci & Engn, Beijing 100029, Peoples R China;[2]East China Univ Sci & Technol, Res Ctr Biomed Mat, Key Lab Ultrafine Mat, State Key Lab Bioreactor Engn,Minist Educ, Shanghai 200237, Peoples R China

年份：2018

卷号：28

期号：40

外文期刊名：ADVANCED FUNCTIONAL MATERIALS

收录：;EI(收录号：20183605779023);WOS:【SCI-EXPANDED(收录号:WOS:000446155700006)】；

基金：X.K.D. and S.D. contributed equally to this work. This work was partially supported by the National Key Research and Development Program of China (Grant No. 2016YFC1100404), National Natural Science Foundation of China (Grant Nos. 21504006, 51573014, and 51733001), Beijing Municipal Natural Science Foundation (Grant Nos. L160004 and 7161001), and the "Eastern Scholar Professorship" from Shanghai local government (TP2014034) to R.L.

语种：英文

外文关键词：antibacterial polymers; cell proliferation; coagulation; hemocompatibility; kill-and-release

摘要：Antibacterial materials that prevent bacterial infections and mitigate bacterial virulence have attracted great scientific interests. In recent decades, the bactericidal polymers have been presented as promising candidates to combat bacterial pathogens, mainly based on the construction of bactericidal cationic polymers, functionalization with biocidal agents, and formation of bacterial-repelling layers. However, these established strategies have inherent disadvantages because they often overlook important features such as their biocompatibility and biosafety, especially for biomedical applications. In recent years, many efforts have been made focusing on the development of multifunctional antibacterial materials to meet the elaborate requirements for medical devices and public hygiene products. Herein the recent advances in developing multifunctional materials for their antibacterial activities together with other functions including kill-and-release capability, hemocompatibility, cell proliferation promoting properties, and coagulation promoting ability for wound dressing are highlighted. In addition, the outlooks on the remaining challenges that should be addressed in the field of multifunctional antibacterial materials are also described.