文献类型：期刊文献

英文题名：Robust Multifunctional Ultrathin 2 Nanometer Organic Nanofibers

作者：Jin, Haibao[1];Wu, Pengchao[1];Liu, Zhenghui[1];Sun, Zichao[1];Feng, Weisheng[1];Ding, Yanhuai[2];Cao, Huiliang[1];Lin, Zhiqun[3];Lin, Shaoliang[1]

机构：[1]East China Univ Sci & Technol, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Mat Sci & Engn, Shanghai Key Lab Adv Polymer Mat, Shanghai 200237, Peoples R China;[2]Xiangtan Univ, Sch Mech Engn & Mech, Xiangtan 411105, Hunan, Peoples R China;[3]Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 117585, Singapore

年份：2024

卷号：18

期号：32

起止页码：21576

外文期刊名：ACS NANO

收录：;EI(收录号：20243216824333);WOS:【SCI-EXPANDED(收录号:WOS:001284118100001)】；

基金：Financial support was provided by the National Natural Science Foundation of China (52373114, 52325308, 52073092, and 22001071). Support by Shanghai Scientific and Technological Innovation Project (19JC1411700) is also appreciated. The authors thank Research Center of Analysis and Test of East China University of Science and Technology for the help on the UPLC-MS characterization. The authors also thank Shanghai Synchrotron Radiation Facility (Beamline BL16B1) for assistance with WAXS data collection. We appreciated Dr. Hao Lv and Dr. Ben Liu at Sichuan University for helping us perform catalytic experiments. We also thank Dr. Lu Meng and Dr. Jinyao Liu at Shanghai Jiao Tong University for the assistance with the bioimaging and antibacterial study.

语种：英文

外文关键词：ultrathin organic nanofiber; azobenzene-based peptoids; self-assembly; photoresponsive feature; multifunctionality

摘要：Ultrathin organic nanofibers (UTONFs) represent an emerging class of nanomaterials as they carry a set of favorable attributes, including ultrahigh specific surface area, lightweight, and mechanical flexibility, over inorganic counterparts, for use in biomedicine and nanotechnology. However, precise synthesis of uniform UTONFs (diameter <= 2 nm) with tailored functionalities remained challenging. Herein, we report robust multifunctional UTONFs using hydrophobic interaction-driven self-assembly of amphiphilic alternating peptoids containing hydrophobic photoresponsive azobenzene and hydrophilic hydroxyl moieties periodically arranged along the peptoid backbone. Notably, the as-crafted UTONFs are approximately 2 nm in diameter and tens of micrometers in length (an aspect ratio, AR, of similar to 10000), exemplifying the UTONFs with the smallest diameter yielded via self-assembly. Intriguingly, UTONFs were disassembled into short-segmented nanofibers and controllably reassembled into UTONFs, resembling "step-growth polymerization". Photoisomerization of azobenzene moieties leads to reversible transformation between UTONFs and spherical micelles. Such meticulously engineered UTONFs demonstrate potential for catalysis, bioimaging, and antibacterial therapeutics. Our study highlights the significance of the rational design of amphiphiles containing alternating hydrophobic and hydrophilic moieties in constructing otherwise unattainable extremely thin UTONFs with ultrahigh AR and stimuli-responsive functionalities for energy and bionanotechnology.