文献类型：期刊文献

英文题名：Rhodium-Catalyzed Addition Cyclization of Hydrazines with Alkynes: Pyrazole Synthesis via Unexpected C-N Bond Cleavage

作者：Li, Deng Yuan;Mao, Xiao Feng;Chen, Hao Jie;Chen, Guo Rong;Liu, Pei Nian[1]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China; E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2014

卷号：16

期号：13

起止页码：3476

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000340808000015)，CCR-EXPANDED(收录号:WOS:000340808000015)】；

基金：This work was supported by NSFC/China, NCET (NCET-13-0798), the Innovation Program of Shanghai Municipal Education Commission (Project No. 12ZZ050), the Basic Research Program of the Shanghai Committee of Sci. & Tech. (Project No. 13NM1400802), and the Fundamental Research Funds for the Central Universities.

语种：英文

摘要：Rhodium-catalyzed addition-cyclization of hydrazines with alkynes has been achieved to afford highly substituted pyrazoles under mild conditions. The cascade reaction involves two transformations: addition of the C-N bond of hydrazines to alkynes via unexpected C-N bond cleavage and intramolecular dehydration cyclization.