文献类型：期刊文献

英文题名：Novel comb-like ionenes with aliphatic side chains: synthesis and antimicrobial properties

作者：Xu, Xiang[1,2];Xiao, Huining[1];Ziaee, Zainab[1];Wang, Hao[1];Guan, Yong[2];Zheng, Anna[2]

机构：[1]Univ New Brunswick, Dept Chem Engn, Fredericton, NB E3B 6C1, Canada;[2]E China Univ Sci & Technol, Key Lab Ultrafine Mat, Minist Educ, Sch Mat Sci & Engn, Shanghai 200237, Peoples R China

年份：2013

卷号：48

期号：3

起止页码：1162

外文期刊名：JOURNAL OF MATERIALS SCIENCE

收录：;EI(收录号：20130115857468);WOS:【SCI-EXPANDED(收录号:WOS:000312904900022)】；

基金：The authors would like to thank NSERC Canada and NSREC Strategic Network, SENTINEL-Bioactive Paper, for funding this research.

语种：英文

外文关键词：Particle size - Solutions - Suspensions (fluids) - Aspergillus - Chains - Microwave integrated circuits

摘要：A series of comb-like ionenes (C-ionenes) with aliphatic side chains were prepared via the Menschutkin reaction from amine, epichlorohydrin, and N, N, N', N'-tetramethyl-1,6-hexanediamine. The structures of the resulting ionenes were characterized by means of charge density, H-1-NMR, and C-13-NMR. The antimicrobial properties of the ionenes were also investigated by measuring the minimum inhibition concentration (MIC) against Escherichia coli (E. coli). The corresponding antimicrobial dynamics were studied by detecting the UV absorbance of the E. coli suspension. It was found that in comparison to the linear ionenes (L-ionenes), C-ionenes exhibited lowerMIC values and faster antimicrobial effect influenced by the side chains. In particular, C-ionene with 4-carbon side chains showed MIC at 7.8 mu g/mL and its aqueous solution (31.2 mu g/mL) inhibited 99.9 % E. coli within 2 min. The morphologies of C-ionenes in aqueous solution were investigated by measuring their particle sizes and zeta potentials. In addition, the anti-mold tests against Aspergillus niger and Chaetomium globosum suggested that the comb-like ionenes were effective at inhibiting the growth of the fungi.