文献类型：期刊文献

英文题名：A Direct Amine-Palladium Acetate Cocatalyzed Saegusa Oxidation Reaction of Unmodified Aldehydes to α,β-Unsaturated Aldehydes

作者：Zhu, Jin[1];Liu, Jie[1];Ma, Ruoqun[1];Xie, Hexin[2];Li, Jian[1];Jiang, Hualiang[1,3];Wang, Wei[1,3]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Univ New Mexico, Dept Chem & Biol Chem, Albuquerque, NM 87131 USA;[3]Chinese Acad Sci, Shanghai Inst Mat Med, Drug Discovery & Design Ctr, Shanghai 201203, Peoples R China

年份：2009

卷号：351

期号：9

起止页码：1229

外文期刊名：ADVANCED SYNTHESIS & CATALYSIS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000267894000005)，CCR-EXPANDED(收录号:WOS:000267894000005)】；

基金：We gratefully acknowledge the financial support from the National Natural Science Foundation of China (Grant 90813005), the 863 Hi-Tech Program of China (Grant 2006AA020404), the China III Project (Grant No. 807023) and Shanghai Rising-Star Program (A type) of Shanghai Ministry of Science and Technology (Grant 07A14013).

语种：英文

外文关键词：aminocatalysis; organocatalysis; Saegusa reaction; alpha,beta-unsaturated aldehydes

摘要：A direct preparation of synthetically useful alpha,beta-unsaturated aldehydes from readily available aldehydes has been developed. The process is effectively cocatalyzed by an amine-palladium acetate to give rise to alpha,beta-unsaturated aldehydes in moderate to good yields (41-62%). The reaction features the use of unmodified aldehydes rather than enol silyl ethers, which are used in a typical Saegusa oxidation reaction.