文献类型：期刊文献

英文题名：Water-soluble bright NIR AIEgens with hybrid ROS for wash-free mitochondrial "off-on" imaging and photodynamic therapy

作者：Xu, Fang-Zhou[1,2];Wang, Cheng-Yun[1,2];Wang, Qi[1,2];Zou, Jian-Wei[3];Qiao, Yi-Jie[1,2];Guo, Zhi-Qian[1,2];Zhao, Weijun[1,2];Zhu, Wei-Hong[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]NingboTech Univ, Ningbo 315100, Zhejiang, Peoples R China

年份：2022

卷号：58

期号：44

起止页码：6393

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;EI(收录号：20222512246424);WOS:【SCI-EXPANDED(收录号:WOS:000793323900001)】；

基金：The authors are grateful to the financial support from the Natural Science Foundation of Shanghai (No. 22ZR1417300), the National Natural Science Foundation of China (No. 22105069).

语种：英文

外文关键词：Infrared devices - Lanthanum compounds - Mitochondria

摘要：Several aggregation-induced emission luminogens (AIEgens) with excellent water-solubility and near-infrared emission were designed and synthesized for wash-free "off-on" mitochondrial imaging and photodynamic therapy of HeLa cells. The AIEgen TEPP exhibits both bright near-infrared emission (phi(F) = 17.8%) and high hybrid ROS productivity (including OH center dot and O-1(2)).