文献类型：期刊文献

英文题名：Copper-Catalyzed Trifluoromethylation and Cyclization of Aromatic-Sulfonyl-Group-Tethered Alkenes for the Construction of 1,2-Benzothiazinane Dioxide Type Compounds

作者：Dong, Xiang[1];Sang, Rui[1];Wang, Qiang[1,2,3];Tang, Xiang-Ying[1];Shi, Min[1,2,3]

机构：[1]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China;[2]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2013

卷号：19

期号：50

起止页码：16910

外文期刊名：CHEMISTRY-A EUROPEAN JOURNAL

收录：;EI(收录号：20135017079505);WOS:【SCI-EXPANDED(收录号:WOS:000327801800008)，CCR-EXPANDED(收录号:WOS:000327801800008)】；

基金：We thank the Shanghai Municipal Committee of Science and Technology (11JC1402600), National Basic Research Program of China (973)-2009CB825300, the Fundamental Research Funds for the Central Universities and the National Natural Science Foundation of China for financial support (21072206, 21302203, 20472096, 21372241, 20672127, 21102166, 20732008 and 21121062).

语种：英文

外文关键词：benzothiazinane; copper; homogeneous catalysis; radicals; trifluoromethylation

摘要：A multi-talented system: An efficient copper-catalyzed tandem trifluoromethylation/annulation of an electron-deficient aromatic ring has been developed. This method provides a powerful and straightforward way to synthesize trifluoromethylated 1,2-benzothiazinane dioxides under mild conditions (see scheme). The mechanism was investigated by a series of kinetic experiments and isotopic labeling studies. ? 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.