文献类型：期刊文献

英文题名：Copper-Mediated Trifluoromethylation Using Phenyl Trifluoromethyl Sulfoxide

作者：Li, Xinjin[1,2];Zhao, Jingwei[2];Zhang, Liang[2];Hu, Mingyou[2];Wang, Limin[1];Hu, Jinbo[2]

机构：[1]E China Univ Sci & Technol, Inst Fine Chem, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

年份：2015

卷号：17

期号：2

起止页码：298

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000348331800033)，CCR-EXPANDED(收录号:WOS:000348331800033)】；

基金：This work was supported by the National Basic Research Program of China (2015CB931900, 2012CB215500), National Natural Science Foundation of China (21421002, 21372246, 21102163, 21272069, and 20825209). We also thank Professor Shizheng Zhu (SIOC) for helpful discussions.

语种：英文

摘要：A new method for the generation of trifluoromethylcopper ("CuCF3") species from readily available phenyl trifluoromethyl sulfoxide has been developed. The "CuCF3" reagent can be applied in efficient trifluoromethylations of aryl iodides and activated aryl bromides in the absence of additional ligands. Furthermore, the "CuCF3" species can also undergo oxidative cross-coupling with terminal alkynes and arylboronic acids.