文献类型：期刊文献

英文题名：A convenient and efficient palladium-catalyzed system for cross-coupling of aryl bromides with active methylene compounds

作者：Gao, CW; Tao, XC; Qian, YL; Huang, JL

机构：[1]E China Univ Sci & Technol, Organomet Chem Lab, Shanghai 200237, Peoples R China

年份：2003

期号：11

起止页码：1716

外文期刊名：SYNLETT

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000185229900034)，CCR-EXPANDED(收录号:WOS:000185229900034)】；

语种：英文

外文关键词：palladium catalysis; cross-coupling; arylmalononitrile; arylcyanoacetate; aryl bromide

摘要：A simply catalytic system containing palladium-phosphine complex, generated in situ from PdCl2/tert-phosphino ligand in pyridine, has been systematically studied in the cross-coupling of bromobenzene with malononitrile or ethyl cyanoacetate anion. The effect of molar ratio of phosphine ligand to PdCl2 on the activity of the coupling was also discussed. It is found that the catalytic system has highly catalytic activity to produce aryl malononitriles and cyanoacetates in considerable yields (67-90%) when the substituted aryl bromides were used as substrates.