文献类型：期刊文献

英文题名：Integration of Esterification and Distillation for Enhanced Production of Dimethyl 2,6-Naphthalenedicarboxylate: Kinetic Modeling, Process Development, and Multiobjective Optimization

作者：Ning, Bo[1];Liu, Yuchen[1];Guo, Wenze[1,2];Cao, Chenxi[2];Li, Jin-Jin[1];Zhao, Ling[1];Xi, Zhenhao[1]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn & Low Carbon Technol, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Key Lab Smart Mfg Energy Chem Proc, Minist Educ, Shanghai 200237, Peoples R China

年份：2026

卷号：65

期号：21

起止页码：10602

外文期刊名：INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

收录：;EI(收录号：20262320854983);WOS:【SCI-EXPANDED(收录号:WOS:001769442800001)】；

基金：This research was financially supported by the National Natural Science Foundation of China (Grant No. 22408099), the Program of Shanghai Leading Talents Overseas for Wenze Guo, and the Fundamental Research Funds for Central Universities.

语种：英文

外文关键词：Distillation - Distillation columns - Esterification - Esters - Kinetic parameters - Kinetic theory - Methyl ester - Naphthalene - Sulfur compounds - Sustainable development

摘要：Dimethyl 2,6-naphthalenedicarboxylate (NDC) is an essential monomer for synthesizing advanced polyesters such as polyethylene naphthalate. To address the need for its efficient and sustainable production, this study establishes an integrated framework combining kinetic modeling, process simulation, and multiobjective optimization for the continuous esterification of 2,6-naphthalenedicarboxylic acid (NDA) with methanol. A robust kinetic model, validated against experimental data obtained with a polymeric ferric sulfate catalyst, accurately describes the reaction across both heterogeneous and homogeneous regimes. Two processes were developed and compared: a conventional sequential esterification-distillation route and an intensified reactive distillation (RD) alternative. A multiobjective optimization minimizing total annual cost and CO2 emissions revealed that the RD-based process significantly simplifies equipment (one reactor, three columns) while maintaining high product purity (>= 0.999), leading to concurrent economic and environmental improvements. This work demonstrates that process intensification via reaction-distillation integration offers a balanced path toward greener chemical manufacturing. The proposed framework is generalizable to other esterification systems involving low-solubility aromatic acids.